Resources

A research group has run multiple musculoskeletal bioengineering projects using organ-on-a-chip and organoid technologies designed to be fully animal-free — with ELAREM™ as the serum surrogate for primary human cells.

“Since 2019, we have initiated many musculoskeletal bioengineering projects using organ-on-a-chip and organoid technologies that aim to be animal-free. ELAREM™ as serum surrogate is ideally suited to provide primary human cells an animal-free environment to proliferate without any performance losses. My research group supports the use of serum substitutes such as ELAREM™ and we won’t ever go back to conventional FBS-based in vitro cultures.”

Dr. Mario Rothbauer · Research Group Leader, Orthopedic Microsystems Unit, Karl Chiari Lab for Orthopaedic Biology, Medical University of Vienna

A hospital cell manufacturing unit produces its investigational ATMP — human mesenchymal stromal cells — with GMP-grade ELAREM™ Perform-FD PLUS, EU origin included for compliance with the European Pharmacopoeia.

“At OUH-CELL-BENCH, we have been manufacturing our investigational ATMP product, ADRC001 (human mesenchymal stromal cells), using GMP-grade ELAREM Perform-FD Plus from PL BioScience for more than a year. We have found this ready-to-use hPL product to support cell growth exceptionally well, and we are particularly satisfied with its EU origin, which ensures full compliance with the European Pharmacopoeia.”

Ditte Caroline Andersen · Professor in Cardiovascular Regeneration, Odense University Hospital / University of Southern Denmark